Thursday, October 1, 2009

Predicted prevalence of diabetes and the incidence of atrial fibrillation in women

Atrial fibrillation is 44% more often and 38% more likely to develop diabetes, if present in an adult population was - especially among women, according to the recently published.

The researchers examined the prevalence and incidence of atrial fibrillation in patients with diabetes and 17,372 for the same amount by age and sex matched controls without diabetes mellitus type 2 diabetes, in a registration Kaiser Permanente Northwest. The researchers followed the patients without atrial fibrillation for comparison of the incidence of atrial fibrillation, while controlling known risk factors. The data showed that the prevalence of atrial fibrillation was significantly higher in patients with diabetes compared to those without (3.6% vs 2.5%, p <.0001).

During a mean follow-up of 7.2 years, patients with diabetes without initially developed atrial fibrillation with age and sex adjusted rate of 9.1 per 1000 person years compared with 6.6 per 1000 person-years in patients without diabetes.

Diabetes was associated with an increased risk of 26% for atrial fibrillation in women after adjustment for other risk factors (HR = 1.26, 95% CI, 1.08-1.46). Diabetes not a risk factor statistically significant in men.

Males had a higher prevalence of atrial fibrillation in all age groups, regardless of diabetes, but the difference in the prevalence in people with diabetes vs without diabetes was higher among women. Atrial auricle is 30% more common in men aged 65 to 74 years with diabetes (7.9% vs 6.1%, p <.037), while the prevalence of atrial fibrillation was 61% higher than in women with diabetes the same age group (6.1% vs 3.8%, p =. 002).

"These results have potential impact on public health, especially women and emphasized the need for further investigation of the mechanical connection between diabetes and atrial fibrillation," write the researchers.

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