Miracle pill, a drug taken by diabetics may slow the aging process
Economic pill taken by millions of diabetics could be the secret to a long and healthy life.
The research suggests that metformin, which costs as little as 2p a tablet, could prolong human life. It may also be able to keep physically agile and mentally strong in old age was found. There are also signs that can help prevent people from putting on weight.
Professor Dominic Withers, from University College London, said the results suggest that it is possible to establish the anti-aging drugs. The researchers based their studies on worms, flies and dogs have shown very low calorie diets tend to live longer, healthier lives. To imitate the effect, without the need for design created mice diet can not make a key protein, called S6K1. Experiments have shown that blocking of S6K1 increases the energy levels of a sensor called AMPK. When you eat less, increase the levels of AMPK, and the body goes into a survival mode and slows the aging process. Metformin, which has been used safely for over 50 years to monitor the levels of blood sugar in age and obesity, diabetes related, was also found to increase levels of A* Britain must charge for the health and increase the retirement age to escape the debt crisis, says IMF
* Half of all children born in Great Britain live to 100, say researchers
* Could a pill to give you back the muscles of your youth?
* Can this little piece of plastic that looks ten years younger?
The tests found that mice of both sexes were healthy, but the effects were stronger than females, who also lived longer.
Their life expectancy has increased by an average of 20 percent. But some saw an increase of over 50 percent, reports the journal Science.
* Britain must charge for the health and increase the retirement age to escape the debt crisis, says IMF
* Half of all children born in Great Britain live to 100, say researchers
* Can a pill that the muscles of the back of your youth?
* Can this little piece of plastic that looks ten years younger?
In 'middle age', the creatures were leaner than normal mice of the same age and had stronger bones and better balance, strength and coordination. They were even more curious, suggesting that they were mentally sharper. It even appears that their immune system stronger and younger. It is expected that metformin can mimic other effects of blocking of S6K1.
Metformin
Elixir of life? Metformin, which costs as little as 2p a tablet, could prolong human life, scientists say
Diabetics that take as its ability to prolong life can be ignored by the effects of the disease.
Professor Withers drug plans to test the capacity anti-aging in mice and hope to begin the first human trials within five years.
These would be likely to be in obese people whose weight puts them at risk of diabetes and other conditions later in life.
The researchers also want to check the ability of the drug to prevent Alzheimer's disease.
Experiments with mice have given encouraging results so far
The success of evaluation: The mice tested lived longer and are healthier
Long history as a safe drug metformin means that I should go through the safety review as part of a new brand name drugs.
But there is probably 15 years ago is widely used to protect against diseases of aging.
Meanwhile, the teacher "strongly recommended healthy adults taking the drug, hoping to prolong his life.
Dr David Gems, said: "We suddenly much closer to the treatment of aging than we thought." We went from the first results in worm models to be "druggable" targets in mice."The next logical step is to see whether metformin can delay the aging process in humans
Economic pill taken by millions of diabetics could be the secret to a long and healthy life.
The research suggests that metformin, which costs as little as 2p a tablet, could prolong human life. It may also be able to keep physically agile and mentally strong in old age was found. There are also signs that can help prevent people from putting on weight.
Professor Dominic Withers, from University College London, said the results suggest that it is possible to establish the anti-aging drugs. The researchers based their studies on worms, flies and dogs have shown very low calorie diets tend to live longer, healthier lives. To imitate the effect, without the need for design created mice diet can not make a key protein, called S6K1. Experiments have shown that blocking of S6K1 increases the energy levels of a sensor called AMPK. When you eat less, increase the levels of AMPK, and the body goes into a survival mode and slows the aging process. Metformin, which has been used safely for over 50 years to monitor the levels of blood sugar in age and obesity, diabetes related, was also found to increase levels of A* Britain must charge for the health and increase the retirement age to escape the debt crisis, says IMF
* Half of all children born in Great Britain live to 100, say researchers
* Could a pill to give you back the muscles of your youth?
* Can this little piece of plastic that looks ten years younger?
The tests found that mice of both sexes were healthy, but the effects were stronger than females, who also lived longer.
Their life expectancy has increased by an average of 20 percent. But some saw an increase of over 50 percent, reports the journal Science.
* Britain must charge for the health and increase the retirement age to escape the debt crisis, says IMF
* Half of all children born in Great Britain live to 100, say researchers
* Can a pill that the muscles of the back of your youth?
* Can this little piece of plastic that looks ten years younger?
In 'middle age', the creatures were leaner than normal mice of the same age and had stronger bones and better balance, strength and coordination. They were even more curious, suggesting that they were mentally sharper. It even appears that their immune system stronger and younger. It is expected that metformin can mimic other effects of blocking of S6K1.
Metformin
Elixir of life? Metformin, which costs as little as 2p a tablet, could prolong human life, scientists say
Diabetics that take as its ability to prolong life can be ignored by the effects of the disease.
Professor Withers drug plans to test the capacity anti-aging in mice and hope to begin the first human trials within five years.
These would be likely to be in obese people whose weight puts them at risk of diabetes and other conditions later in life.
The researchers also want to check the ability of the drug to prevent Alzheimer's disease.
Experiments with mice have given encouraging results so far
The success of evaluation: The mice tested lived longer and are healthier
Long history as a safe drug metformin means that I should go through the safety review as part of a new brand name drugs.
But there is probably 15 years ago is widely used to protect against diseases of aging.
Meanwhile, the teacher "strongly recommended healthy adults taking the drug, hoping to prolong his life.
Dr David Gems, said: "We suddenly much closer to the treatment of aging than we thought." We went from the first results in worm models to be "druggable" targets in mice."The next logical step is to see whether metformin can delay the aging process in humans
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